Origin and differentiation trajectories of fibroblastic reticular cells in the splenic white pulp

Origin and differentiation trajectories of fibroblastic reticular cells in the splenic white pulp

The white pulp of spleen is an important immune structure dynamically modulated during development and immune responses. Here the authors define, using multi-color lineage tracing and single-cell transcriptome analysis, the subset distribution and differentiation trajectory of fibroblastic reticular...

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Bibliographic Details
Main Authors: Hung-Wei Cheng, Lucas Onder, Mario Novkovic, Charlotte Soneson, Mechthild Lütge, Natalia Pikor, Elke Scandella, Mark D. Robinson, Jun-ichi Miyazaki, Anne Tersteegen, Ursula Sorg, Klaus Pfeffer, Thomas Rülicke, Thomas Hehlgans, Burkhard Ludewig
Format: Article
Language:English
Published: Nature Publishing Group 2019-04-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-019-09728-3

Internet

https://doi.org/10.1038/s41467-019-09728-3

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