Quantitative principles of cis-translational control by general mRNA sequence features in eukaryotes

Quantitative principles of cis-translational control by general mRNA sequence features in eukaryotes

Abstract Background General translational cis-elements are present in the mRNAs of all genes and affect the recruitment, assembly, and progress of preinitiation complexes and the ribosome under many physiological states. These elements include mRNA folding, upstream open reading frames, specific nuc...

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Bibliographic Details
Main Authors: Jingyi Jessica Li, Guo-Liang Chew, Mark Douglas Biggin
Format: Article
Language:English
Published: BMC 2019-08-01
Series:Genome Biology
Subjects:
Translation
Cis-control
RNA structure
Codon usage
Collinear regulation
Online Access:http://link.springer.com/article/10.1186/s13059-019-1761-9

Internet

http://link.springer.com/article/10.1186/s13059-019-1761-9

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