KRAS-MEK Signaling Controls Ago2 Sorting into Exosomes

KRAS-MEK Signaling Controls Ago2 Sorting into Exosomes

Secretion of RNAs in extracellular vesicles is a newly recognized form of intercellular communication. A potential regulatory protein for microRNA (miRNA) secretion is the critical RNA-induced silencing complex (RISC) component Argonaute 2 (Ago2). Here, we use isogenic colon cancer cell lines to sho...

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Bibliographic Details
Main Authors: Andrew J. McKenzie, Daisuke Hoshino, Nan Hyung Hong, Diana J. Cha, Jeffrey L. Franklin, Robert J. Coffey, James G. Patton, Alissa M. Weaver
Format: Article
Language:English
Published: Elsevier 2016-05-01
Series:Cell Reports
Subjects:
exosomes
extracellular vesicles
miRNA
Argonaute
extracellular RNA
signaling
Online Access:http://www.sciencedirect.com/science/article/pii/S2211124716303874

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http://www.sciencedirect.com/science/article/pii/S2211124716303874

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