KRAS-MEK Signaling Controls Ago2 Sorting into Exosomes
Secretion of RNAs in extracellular vesicles is a newly recognized form of intercellular communication. A potential regulatory protein for microRNA (miRNA) secretion is the critical RNA-induced silencing complex (RISC) component Argonaute 2 (Ago2). Here, we use isogenic colon cancer cell lines to sho...
Main Authors: | Andrew J. McKenzie, Daisuke Hoshino, Nan Hyung Hong, Diana J. Cha, Jeffrey L. Franklin, Robert J. Coffey, James G. Patton, Alissa M. Weaver |
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Format: | Article |
Language: | English |
Published: |
Elsevier
2016-05-01
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Series: | Cell Reports |
Subjects: | |
Online Access: | http://www.sciencedirect.com/science/article/pii/S2211124716303874 |
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