Evaluation of the expression levels of BRAF V600E mRNA in primary tumors of thyroid cancer using an ultrasensitive mutation assay

Evaluation of the expression levels of BRAF V600E mRNA in primary tumors of thyroid cancer using an ultrasensitive mutation assay

Abstract Background The BRAF V600E gene encodes for the mutant BRAFV600E protein, which triggers downstream oncogenic signaling in thyroid cancer. Since most currently available methods have focused on detecting BRAF V600E mutations in tumor DNA, there is limited information about the level of BRAF...

Full description

Bibliographic Details
Main Authors: Tien Viet Tran, Kien Xuan Dang, Quynh Huong Pham, Ung Dinh Nguyen, Nhung Thi Trang Trinh, Luong Van Hoang, Son Anh Ho, Ba Van Nguyen, Duc Trong Nguyen, Dung Tuan Trinh, Dung Ngoc Tran, Arto Orpana, Ulf-Håkan Stenman, Jakob Stenman, Tho Huu Ho
Format: Article
Language:English
Published: BMC 2020-05-01
Series:BMC Cancer
Subjects:
Thyroid cancer
BRAF mutation
mRNA mutation assay
Diagnosis
Online Access:http://link.springer.com/article/10.1186/s12885-020-06862-w

Internet

http://link.springer.com/article/10.1186/s12885-020-06862-w

Similar Items