A neutralizing anti-gH/gL monoclonal antibody is protective in the guinea pig model of congenital CMV infection.

A neutralizing anti-gH/gL monoclonal antibody is protective in the guinea pig model of congenital CMV infection.

Human cytomegalovirus (HCMV) is the most common cause of congenital virus infection. Congenital HCMV infection occurs in 0.2-1% of all births, and causes birth defects and developmental abnormalities, including sensorineural hearing loss and developmental delay. Several key studies have established...

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Bibliographic Details
Main Authors: Marcy R Auerbach, Donghong Yan, Rajesh Vij, Jo-Anne Hongo, Gerald Nakamura, Jean-Michel Vernes, Y Gloria Meng, Samantha Lein, Pamela Chan, Jed Ross, Richard Carano, Rong Deng, Nicholas Lewin-Koh, Min Xu, Becket Feierbach
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-04-01
Series:PLoS Pathogens
Online Access:http://europepmc.org/articles/PMC3983071?pdf=render

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http://europepmc.org/articles/PMC3983071?pdf=render

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