Versican modulates tumor-associated macrophage properties to stimulate mesothelioma growth

Versican modulates tumor-associated macrophage properties to stimulate mesothelioma growth

Versican promotes experimental tumor growth through cell- and non cell-autonomous mechanisms. Its role in mesothelioma progression has not been investigated so far. In this study we investigated the impact of tumor-derived versican in mesothelioma progression and the underlying mechanism of its acti...

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Bibliographic Details
Main Authors: Apostolos G. Pappas, Sophia Magkouta, Ioannis S. Pateras, Ioannis Skianis, Charalampos Moschos, Maria Eleni Vazakidou, Katherina Psarra, Vassilis G. Gorgoulis, Ioannis Kalomenidis
Format: Article
Language:English
Published: Taylor & Francis Group 2019-02-01
Series:OncoImmunology
Subjects:
chondroitin sulfate proteoglycan core protein 2
pleural neoplasms
monocytes/macrophages
extra-cellular matrix
tumor-immunology
Online Access:http://dx.doi.org/10.1080/2162402X.2018.1537427

Internet

http://dx.doi.org/10.1080/2162402X.2018.1537427

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