The Nociceptin Receptor (NOP) Agonist AT-312 Blocks Acquisition of Morphine- and Cocaine-Induced Conditioned Place Preference in Mice

The Nociceptin Receptor (NOP) Agonist AT-312 Blocks Acquisition of Morphine- and Cocaine-Induced Conditioned Place Preference in Mice

Treatment of drug addiction remains an unmet medical need due to the dearth of approved pharmacotherapies. There are no approved treatments for cocaine addiction, whereas the current opioid crisis has revealed the stark reality of the limited options to treat prescription and illicit opioid abuse. P...

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Bibliographic Details
Main Authors: Nurulain T. Zaveri, Paul V. Marquez, Michael E. Meyer, Abdul Hamid, Kabirullah Lutfy
Format: Article
Language:English
Published: Frontiers Media S.A. 2018-11-01
Series:Frontiers in Psychiatry
Subjects:
morphine
cocaine
conditioned place preference
AT-312
NOP agonist
NOP receptor knockout
Online Access:https://www.frontiersin.org/article/10.3389/fpsyt.2018.00638/full

Internet

https://www.frontiersin.org/article/10.3389/fpsyt.2018.00638/full

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