Independent interactions of phosphorylated β-catenin with E-cadherin at cell-cell contacts and APC at cell protrusions.

The APC tumour suppressor functions in several cellular processes including the regulation of β-catenin in Wnt signalling and in cell adhesion and migration.In this study, we establish that in epithelial cells N-terminally phosphorylated β-catenin specifically localises to several subcellular sites...

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Bibliographic Details
Main Authors: Maree C Faux, Janine L Coates, Nadia J Kershaw, Meredith J Layton, Antony W Burgess
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2010-11-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC2994709?pdf=render