Urate inhibits microglia activation to protect neurons in an LPS-induced model of Parkinson’s disease
Abstract Background Multiple risk factors contribute to the progression of Parkinson’s disease, including oxidative stress and neuroinflammation. Epidemiological studies have revealed a link between higher urate level and a lower risk of developing PD. However, the mechanistic basis for this associa...
Main Authors: | , , , , , , , |
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Format: | Article |
Language: | English |
Published: |
BMC
2018-05-01
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Series: | Journal of Neuroinflammation |
Subjects: | |
Online Access: | http://link.springer.com/article/10.1186/s12974-018-1175-8 |