Bioengineered Viral Platform for Intramuscular Passive Vaccine Delivery to Human Skeletal Muscle

Bioengineered Viral Platform for Intramuscular Passive Vaccine Delivery to Human Skeletal Muscle

Skeletal muscle is ideal for passive vaccine administration as it is easily accessible by intramuscular injection. Recombinant adeno-associated virus (rAAV) vectors are in consideration for passive vaccination clinical trials for HIV and influenza. However, greater human skeletal muscle transduction...

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Bibliographic Details
Main Authors: Nicole K. Paulk, Katja Pekrun, Gregory W. Charville, Katie Maguire-Nguyen, Michael N. Wosczyna, Jianpeng Xu, Yue Zhang, Leszek Lisowski, Bryan Yoo, Jose G. Vilches-Moure, Gordon K. Lee, Joseph B. Shrager, Thomas A. Rando, Mark A. Kay
Format: Article
Language:English
Published: Elsevier 2018-09-01
Series:Molecular Therapy: Methods & Clinical Development
Online Access:http://www.sciencedirect.com/science/article/pii/S2329050118300536

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http://www.sciencedirect.com/science/article/pii/S2329050118300536

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