Drug-induced cell cycle modulation leading to cell-cycle arrest, nuclear mis-segregation, or endoreplication

<p>Abstract</p> <p>Background</p> <p>Cancer cell responses to chemotherapeutic agents vary, and this may reflect different defects in DNA repair, cell-cycle checkpoints, and apoptosis control. Cytometry analysis only quantifies dye-incorporation to examine DNA content a...

Full description

Bibliographic Details
Main Authors: Kobayashi Tamiyo, Sakaue-Sawano Asako, Ohtawa Kenji, Miyawaki Atsushi
Format: Article
Language:English
Published: BMC 2011-01-01
Series:BMC Cell Biology
Online Access:http://www.biomedcentral.com/1471-2121/12/2