Study of Melatonin as Preventive Agent of Gastrointestinal Damage Induced by Sodium Diclofenac

Safety profile of nonsteroidal anti-inflammatory drugs (NSAIDs) has been widely studied and both therapeutic and side effects at the gastric and cardiovascular level have been generally associated with the inhibitory effect of isoform 1 (COX-1) and 2 (COX-2) cyclooxygenase enzymes. Now there are evi...

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Bibliographic Details
Main Authors: Aroha B. Sánchez, Beatriz Clares, María J. Rodríguez-Lagunas, María J. Fábrega, Ana C. Calpena
Format: Article
Language:English
Published: MDPI AG 2020-01-01
Series:Cells
Subjects:
Online Access:https://www.mdpi.com/2073-4409/9/1/180