The loss of NKX3.1 expression in testicular – and prostate – cancers is not caused by promoter hypermethylation

<p>Abstract</p> <p>Background</p> <p>Recent studies have demonstrated that the NKX3.1 protein is commonly down-regulated in testicular germ cell tumors (TGCTs) and prostate carcinomas. The homeobox gene <it>NKX3.1 </it>maps to chromosome band 8p21, which is...

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Bibliographic Details
Main Authors: Esteller Manel, Saatcioglu Fahri, Henrique Rui, Abeler Vera M, Fraga Mario F, Skotheim Rolf I, Lind Guro E, Teixeira Manuel R, Lothe Ragnhild A
Format: Article
Language:English
Published: BMC 2005-02-01
Series:Molecular Cancer
Online Access:http://www.molecular-cancer.com/content/4/1/8