Immune Differentiation Regulator p100 Tunes NF-κB Responses to TNF

Immune Differentiation Regulator p100 Tunes NF-κB Responses to TNF

Tumor necrosis factor (TNF) is a pleiotropic cytokine whose primary physiological function involves coordinating inflammatory and adaptive immune responses. However, uncontrolled TNF signaling causes aberrant inflammation and has been implicated in several human ailments. Therefore, an understanding...

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Bibliographic Details
Main Authors: Budhaditya Chatterjee, Payel Roy, Uday Aditya Sarkar, Mingming Zhao, Yashika Ratra, Amit Singh, Meenakshi Chawla, Supriyo De, James Gomes, Ranjan Sen, Soumen Basak
Format: Article
Language:English
Published: Frontiers Media S.A. 2019-05-01
Series:Frontiers in Immunology
Subjects:
TNF
pulsatile
NF-kappaB
p100
temporal control
gene-expression specificity
Online Access:https://www.frontiersin.org/article/10.3389/fimmu.2019.00997/full

Internet

https://www.frontiersin.org/article/10.3389/fimmu.2019.00997/full

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