Effects of noise and time delay on E2F's expression level in a bistable Rb‐E2F gene’s regulatory network
Abstract The bistable Rb‐E2F gene regulatory network plays a central role in regulating cellular proliferation‐quiescence transition. Based on Gillespie's chemical Langevin method, the stochastic bistable Rb‐E2F gene’s regulatory network with time delays is proposed. It is found that under the...
| Main Authors: | , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Wiley
2021-06-01
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| Series: | IET Systems Biology |
| Online Access: | https://doi.org/10.1049/syb2.12017 |