Genomic positional conservation identifies topological anchor point RNAs linked to developmental loci

Genomic positional conservation identifies topological anchor point RNAs linked to developmental loci

Abstract Background The mammalian genome is transcribed into large numbers of long noncoding RNAs (lncRNAs), but the definition of functional lncRNA groups has proven difficult, partly due to their low sequence conservation and lack of identified shared properties. Here we consider promoter conserva...

Full description

Bibliographic Details
Main Authors: Paulo P. Amaral, Tommaso Leonardi, Namshik Han, Emmanuelle Viré, Dennis K. Gascoigne, Raúl Arias-Carrasco, Magdalena Büscher, Luca Pandolfini, Anda Zhang, Stefano Pluchino, Vinicius Maracaja-Coutinho, Helder I. Nakaya, Martin Hemberg, Ramin Shiekhattar, Anton J. Enright, Tony Kouzarides
Format: Article
Language:English
Published: BMC 2018-03-01
Series:Genome Biology
Subjects:
lncRNAs
Development
Chromatin architecture
Topology
Zinc finger
Cancer
Online Access:http://link.springer.com/article/10.1186/s13059-018-1405-5

Internet

http://link.springer.com/article/10.1186/s13059-018-1405-5

Similar Items