Effect of shear stress on iPSC-derived human brain microvascular endothelial cells (dhBMECs)

Abstract Background The endothelial cells that form the lumen of capillaries and microvessels are an important component of the blood–brain barrier. Cell phenotype is regulated by transducing a range of biomechanical and biochemical signals in the local microenvironment. Here we report on the role o...

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Bibliographic Details
Main Authors: Jackson G. DeStefano, Zinnia S. Xu, Ashley J. Williams, Nahom Yimam, Peter C. Searson
Format: Article
Language:English
Published: BMC 2017-08-01
Series:Fluids and Barriers of the CNS
Subjects:
Online Access:http://link.springer.com/article/10.1186/s12987-017-0068-z