Diversity in Androgen Receptor Action Among Treatment-naïve Prostate Cancers Is Reflected in Treatment Response Predictions and Molecular Subtypes

Diversity in Androgen Receptor Action Among Treatment-naïve Prostate Cancers Is Reflected in Treatment Response Predictions and Molecular Subtypes

Background: Metastatic prostate cancer (CaP) treatments are evolving rapidly but without evidence-based biomarkers to predict responses, and to maximize remissions and survival. Objective: To determine the activity of androgen receptor (AR), the target for default first-line systemic treatment, in l...

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Bibliographic Details
Main Authors: Salma Ben-Salem, Qiang Hu, Yang Liu, Mohammed Alshalalfa, Xin Zhao, Irene Wang, Varadha Balaji Venkadakrishnan, Dhirodatta Senapati, Sangeeta Kumari, Deli Liu, Andrea Sboner, Christopher E. Barbieri, Felix Feng, Jean-Noel Billaud, Elai Davicioni, Song Liu, Hannelore V. Heemers
Format: Article
Language:English
Published: Elsevier 2020-12-01
Series:European Urology Open Science
Subjects:
Disease stratification
Treatment response
Hormonal therapy
Chemotherapy
Radiotherapy
Biomarker
Online Access:http://www.sciencedirect.com/science/article/pii/S266616832035833X

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http://www.sciencedirect.com/science/article/pii/S266616832035833X

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