Target of Rapamycin Complex 1 (TORC1), Protein Kinase A (PKA) and Cytosolic pH Regulate a Transcriptional Circuit for Lipid Droplet Formation

Target of Rapamycin Complex 1 (TORC1), Protein Kinase A (PKA) and Cytosolic pH Regulate a Transcriptional Circuit for Lipid Droplet Formation

Lipid droplets (LDs) are ubiquitous organelles that fulfill essential roles in response to metabolic cues. The identification of several neutral lipid synthesizing and regulatory protein complexes have propelled significant advance on the mechanisms of LD biogenesis in the endoplasmic reticulum (ER)...

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Bibliographic Details
Main Authors: Vitor Teixeira, Telma S. Martins, William A. Prinz, Vítor Costa
Format: Article
Language:English
Published: MDPI AG 2021-08-01
Series:International Journal of Molecular Sciences
Subjects:
lipid droplet
membrane biogenesis
nutrient
cell signaling
transcription
Online Access:https://www.mdpi.com/1422-0067/22/16/9017

Internet

https://www.mdpi.com/1422-0067/22/16/9017

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