An automated quantitative analysis of cell, nucleus and focal adhesion morphology.

Adherent cells sense the physical properties of their environment via focal adhesions. Improved understanding of how cells sense and response to their physical surroundings is aided by quantitative evaluation of focal adhesion size, number, orientation, and distribution in conjunction with the morph...

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Bibliographic Details
Main Authors: Antonetta B C Buskermolen, Nicholas A Kurniawan, Carlijn V C Bouten
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2018-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC5877879?pdf=render