Human antimicrobial peptide, LL-37, induces non-inheritable reduced susceptibility to vancomycin in Staphylococcus aureus

Abstract Antimicrobial peptides (AMPs) are central components of the innate immune system providing protection against pathogens. Yet, serum and tissue concentrations vary between individuals and with disease conditions. We demonstrate that the human AMP LL-37 lowers the susceptibility to vancomycin...

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Bibliographic Details
Main Authors: Cathrine Friberg, Jakob Krause Haaber, Martin Vestergaard, Anaëlle Fait, Veronique Perrot, Bruce R. Levin, Hanne Ingmer
Format: Article
Language:English
Published: Nature Publishing Group 2020-08-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-020-69962-4