Non-targeting control for MISSION shRNA library silences SNRPD3 leading to cell death or permanent growth arrest

Non-targeting control for MISSION shRNA library silences SNRPD3 leading to cell death or permanent growth arrest

In parallel with the expansion of RNA interference (RNAi) techniques, accumulating evidence indicates that RNAi analyses might be seriously biased due to the off-target effects of gene-specific short hairpin RNAs (shRNAs). Our findings indicated that off-target effects of non-targeting shRNA compris...

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Bibliographic Details
Main Authors: Maria Czarnek, Katarzyna Sarad, Agnieszka Karaś, Jakub Kochan, Joanna Bereta
Format: Article
Language:English
Published: Elsevier 2021-12-01
Series:Molecular Therapy: Nucleic Acids
Subjects:
RNA interference
shRNA
TRC shRNA library
MISSION shRNA library
SHC016 non-targeting shRNA
SNRPD3
Online Access:http://www.sciencedirect.com/science/article/pii/S216225312100233X

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http://www.sciencedirect.com/science/article/pii/S216225312100233X

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