Characterization of the SNAG and SLUG domains of Snail2 in the repression of E-cadherin and EMT induction: modulation by serine 4 phosphorylation.

Characterization of the SNAG and SLUG domains of Snail2 in the repression of E-cadherin and EMT induction: modulation by serine 4 phosphorylation.

Snail1 and Snail2, two highly related members of the Snail superfamily, are direct transcriptional repressors of E-cadherin and EMT inducers. Previous comparative gene profiling analyses have revealed important differences in the gene expression pattern regulated by Snail1 and Snail2, indicating fun...

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Bibliographic Details
Main Authors: Patricia Molina-Ortiz, Ana Villarejo, Matthew MacPherson, Vanesa Santos, Amalia Montes, Serhiy Souchelnytskyi, Francisco Portillo, Amparo Cano
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3342263?pdf=render

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http://europepmc.org/articles/PMC3342263?pdf=render

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