Pneumococcal serotype-specific antibodies persist through early childhood after infant immunization: follow-up from a randomized controlled trial.

In a previous UK multi-center randomized study 278 children received three doses of 7-valent (PCV-7) or 13-valent (PCV-13) pneumococcal conjugate vaccine at 2, 4 and 12 months of age. At 13 months of age, most of these children had pneumococcal serotype-specific IgG concentrations ≥ 0.35 µg/ml and o...

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Bibliographic Details
Main Authors: Johannes Trück, Matthew D Snape, Florencia Tatangeli, Merryn Voysey, Ly-Mee Yu, Saul N Faust, Paul T Heath, Adam Finn, Andrew J Pollard
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3950188?pdf=render