Benzyl-2-Acetamido-2-Deoxy-α-d-Galactopyranoside Increases Human Immunodeficiency Virus Replication and Viral Outgrowth Efficacy In Vitro

Benzyl-2-Acetamido-2-Deoxy-α-d-Galactopyranoside Increases Human Immunodeficiency Virus Replication and Viral Outgrowth Efficacy In Vitro

Glycosylation of host and viral proteins is an important posttranslational modification needed to ensure correct function of glycoproteins. For this reason, we asked whether inhibition of O-glycosylation during human immunodeficiency virus (HIV) in vitro replication could affect HIV infectivity and...

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Bibliographic Details
Main Authors: Alex Olvera, Javier P. Martinez, Maria Casadellà, Anuska Llano, Míriam Rosás, Beatriz Mothe, Marta Ruiz-Riol, Gemma Arsequell, Gregorio Valencia, Marc Noguera-Julian, Roger Paredes, Andreas Meyerhans, Christian Brander
Format: Article
Language:English
Published: Frontiers Media S.A. 2018-01-01
Series:Frontiers in Immunology
Subjects:
human immunodeficiency virus-1
benzyl-2-acetamido-2-deoxy-α-d-galactopyranoside
O-glycosylation
viral outgrowth
replication
infectivity
Online Access:http://journal.frontiersin.org/article/10.3389/fimmu.2017.02010/full

Internet

http://journal.frontiersin.org/article/10.3389/fimmu.2017.02010/full

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