Nitrite-mediated reduction of macrophage NADPH oxidase activity is dependent on xanthine oxidoreductase-derived nitric oxide but independent of S-nitrosation

Nitrite-mediated reduction of macrophage NADPH oxidase activity is dependent on xanthine oxidoreductase-derived nitric oxide but independent of S-nitrosation

Background: Inorganic nitrite has shown beneficial effects in cardiovascular and metabolic diseases partly via attenuation of NADPH-oxidase (NOX)-mediated oxidative stress. However, the exact mechanisms are still unclear. Here we investigated the role of S-nitrosation or altered expression of NOX su...

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Bibliographic Details
Main Authors: Christa Zollbrecht, A. Erik G. Persson, Jon O. Lundberg, Eddie Weitzberg, Mattias Carlström
Format: Article
Language:English
Published: Elsevier 2016-12-01
Series:Redox Biology
Subjects:
NADPH oxidase
Nitrite
Nitric oxide
Oxidative stress
S-nitrosation
Xanthine oxidoreductase
Online Access:http://www.sciencedirect.com/science/article/pii/S2213231716300702

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http://www.sciencedirect.com/science/article/pii/S2213231716300702

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