Evolution of the genetic code: partial optimization of a random code for robustness to translation error in a rugged fitness landscape

<p>Abstract</p> <p>Background</p> <p>The standard genetic code table has a distinctly non-random structure, with similar amino acids often encoded by codons series that differ by a single nucleotide substitution, typically, in the third or the first position of the codo...

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Bibliographic Details
Main Authors: Koonin Eugene V, Wolf Yuri I, Novozhilov Artem S
Format: Article
Language:English
Published: BMC 2007-10-01
Series:Biology Direct
Online Access:http://www.biology-direct.com/content/2/1/24