Understanding human-Plasmodium falciparum immune interactions uncovers the immunological role of worms.

BACKGROUND: Former studies have pointed to a monocyte-dependent effect of antibodies in protection against malaria and thereby to cytophilic antibodies IgG1 and IgG3, which trigger monocyte receptors. Field investigations have further documented that a switch from non-cytophilic to cytophilic classe...

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Bibliographic Details
Main Authors: Christian Roussilhon, Philippe Brasseur, Patrice Agnamey, Jean-Louis Pérignon, Pierre Druilhe
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2010-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC2824820?pdf=render