Brain Tumor Microenvironment and Angiogenesis in Melanoma Brain Metastases

Brain Tumor Microenvironment and Angiogenesis in Melanoma Brain Metastases

BackgroundHigh tumor-infiltrating lymphocytes (TILs) and hemorrhage are important prognostic factors in patients who have undergone craniotomy for melanoma brain metastases (MBM) before 2011 at the University of Pittsburgh Medical Center (UPMC). We have investigated the prognostic or predictive role...

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Bibliographic Details
Main Authors: Dimitri G. Trembath, Eric S. Davis, Shanti Rao, Evan Bradler, Angelica F. Saada, Bentley R. Midkiff, Anna C. Snavely, Matthew G. Ewend, Frances A. Collichio, Carrie B. Lee, Georgia-Sofia Karachaliou, Fatih Ayvali, David W. Ollila, Michal T. Krauze, John M. Kirkwood, Benjamin G. Vincent, Nana Nikolaishvilli-Feinberg, Stergios J. Moschos
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-01-01
Series:Frontiers in Oncology
Subjects:
melanoma brain metastases
vascular endothelial growth factor
basic fibroblast growth factor
tumor infiltrating lymphocytes
CD31
pericyte
Online Access:https://www.frontiersin.org/articles/10.3389/fonc.2020.604213/full

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https://www.frontiersin.org/articles/10.3389/fonc.2020.604213/full

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