The p53 Tumor Suppressor in the Control of Metabolism and Ferroptosis

The p53 tumor suppressor continues to be distinguished as the most frequently mutated gene in human cancer. It is widely believed that the ability of p53 to induce senescence and programmed cell death underlies the tumor suppressor functions of p53. However, p53 has a number of other functions that...

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Bibliographic Details
Main Authors: Keerthana Gnanapradeepan, Subhasree Basu, Thibaut Barnoud, Anna Budina-Kolomets, Che-Pei Kung, Maureen E. Murphy
Format: Article
Language:English
Published: Frontiers Media S.A. 2018-04-01
Series:Frontiers in Endocrinology
Subjects:
p53
Online Access:http://journal.frontiersin.org/article/10.3389/fendo.2018.00124/full