LINE-1 hypermethylation in white blood cell DNA is associated with high-grade cervical intraepithelial neoplasia

LINE-1 hypermethylation in white blood cell DNA is associated with high-grade cervical intraepithelial neoplasia

Abstract Background Long Interspersed Nuclear Elements-1 (LINEs-1) methylation from white blood cells (WBCs) DNA has been proposed as biomarker associated with different types of cancer. The aim of the present study was to investigate the degree of WBCs LINE-1 methylation, according to high-risk Hum...

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Bibliographic Details
Main Authors: Martina Barchitta, Annalisa Quattrocchi, Andrea Maugeri, Carolina Canto, Nadia La Rosa, Maria Antonietta Cantarella, Giuseppa Spampinato, Aurora Scalisi, Antonella Agodi
Format: Article
Language:English
Published: BMC 2017-08-01
Series:BMC Cancer
Subjects:
LINE-1 methylation
Global DNA methylation
Hypermethylation
Cervical cancer
Cervical Intraepitelial Neoplasia
ROC curve analysis
Online Access:http://link.springer.com/article/10.1186/s12885-017-3582-0

Internet

http://link.springer.com/article/10.1186/s12885-017-3582-0

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