Purified Vitexin Compound 1 Inhibits UVA-Induced Cellular Senescence in Human Dermal Fibroblasts by Binding Mitogen-Activated Protein Kinase 1

Purified Vitexin Compound 1 Inhibits UVA-Induced Cellular Senescence in Human Dermal Fibroblasts by Binding Mitogen-Activated Protein Kinase 1

Purified vitexin compound 1 (VB1), a novel lignanoid isolated from the seeds of the Chinese herb Vitex negundo, has strong antioxidant abilities and broad antitumor activities. However, little is known about its anti-photoaging effect on the skin and the underlying mechanism. Here, we demonstrated t...

Full description

Bibliographic Details
Main Authors: Ben Wang, Sha Yan, Yuxin Yi, Yingxue Huang, Zhili Deng, Yiya Zhang, Qingchuan Zheng, Hongfu Xie, Ji Li
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-07-01
Series:Frontiers in Cell and Developmental Biology
Subjects:
purified vitexin compound 1
VB1
senescence
skin photoaging
MAPK1
Online Access:https://www.frontiersin.org/article/10.3389/fcell.2020.00691/full

Internet

https://www.frontiersin.org/article/10.3389/fcell.2020.00691/full

Similar Items