Drug Repurposing to Identify a Synergistic High-Order Drug Combination to Treat Sunitinib-Resistant Renal Cell Carcinoma

Drug Repurposing to Identify a Synergistic High-Order Drug Combination to Treat Sunitinib-Resistant Renal Cell Carcinoma

Repurposed drugs have been evaluated for the management of clear cell renal cell carcinoma (ccRCC), but only a few have influenced the overall survival of patients with advanced disease. To combine repurposed non-oncology with oncological drugs, we applied our validated phenotypic method, which cons...

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Bibliographic Details
Main Authors: Magdalena Rausch, Adriano Rutz, Pierre-Marie Allard, Céline Delucinge-Vivier, Mylène Docquier, Olivier Dormond, Paul J. Dyson, Jean-Luc Wolfender, Patrycja Nowak-Sliwinska
Format: Article
Language:English
Published: MDPI AG 2021-08-01
Series:Cancers
Subjects:
drug combination
drug-drug interaction
drug repurposing
metabolism
metformin
Rapta-C
Online Access:https://www.mdpi.com/2072-6694/13/16/3978

Internet

https://www.mdpi.com/2072-6694/13/16/3978

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