Functional Characterization of New Polyketide Synthase Genes Involved in Ochratoxin A Biosynthesis in Aspergillus Ochraceus fc-1

Functional Characterization of New Polyketide Synthase Genes Involved in Ochratoxin A Biosynthesis in Aspergillus Ochraceus fc-1

Ochratoxin A (OTA), a potentially carcinogenic mycotoxin which contaminates grains, is produced by several Aspergillus species. A comparative sequence analysis of the OTA-producing Aspergillus ochraceus fc-1 strain and other Aspergillus species was performed. Two new OTA-related polyketide synthase...

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Bibliographic Details
Main Authors: Liuqing Wang, Yan Wang, Qi Wang, Fei Liu, Jonathan Nimal Selvaraj, Lingna Liu, Fuguo Xing, Yueju Zhao, Lu Zhou, Yang Liu
Format: Article
Language:English
Published: MDPI AG 2015-07-01
Series:Toxins
Subjects:
ochratoxin A
polyketide synthase
homologous recombination
biosynthetic pathway
Online Access:http://www.mdpi.com/2072-6651/7/8/2723

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http://www.mdpi.com/2072-6651/7/8/2723

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