An inactivated recombinant rabies virus displaying the Zika virus prM-E induces protective immunity against both pathogens.

The global spread of Zika virus (ZIKV), which caused a pandemic associated with Congenital Zika Syndrome and neuropathology in newborns and adults, prompted the pursuit of a safe and effective vaccine. Here, three kinds of recombinant rabies virus (RABV) encoding the prM-E protein of ZIKV were const...

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Bibliographic Details
Main Authors: Hongli Jin, Cuicui Jiao, Zengguo Cao, Pei Huang, Hang Chi, Yujie Bai, Di Liu, Jianzhong Wang, Na Feng, Nan Li, Yongkun Zhao, Tiecheng Wang, Yuwei Gao, Songtao Yang, Xianzhu Xia, Hualei Wang
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2021-06-01
Series:PLoS Neglected Tropical Diseases
Online Access:https://doi.org/10.1371/journal.pntd.0009484