A Critical Role of Autophagy in Regulating Microglia Polarization in Neurodegeneration

A Critical Role of Autophagy in Regulating Microglia Polarization in Neurodegeneration

Neuroinflammation and autophagy dysfunction are closely related to the development of neurodegeneration such as Parkinson’s disease (PD). However, the role of autophagy in microglia polarization and neuroinflammation is poorly understood. TNF-α, which is highly toxic to dopaminergic neurons, is impl...

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Bibliographic Details
Main Authors: Meng-meng Jin, Fen Wang, Di Qi, Wen-wen Liu, Chao Gu, Cheng-Jie Mao, Ya-Ping Yang, Zhong Zhao, Li-Fang Hu, Chun-Feng Liu
Format: Article
Language:English
Published: Frontiers Media S.A. 2018-11-01
Series:Frontiers in Aging Neuroscience
Subjects:
microglia polarization
TNF-α
autophagy
inflammation
neurodegeneration
Online Access:https://www.frontiersin.org/article/10.3389/fnagi.2018.00378/full

Internet

https://www.frontiersin.org/article/10.3389/fnagi.2018.00378/full

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