Primary myelofibrosis: own experience and news from diagnostic and treatment

Primary myelofibrosis: own experience and news from diagnostic and treatment

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<p>The newest advances in primary myelofibrosis (PMF) pathogenesis study, diagnostic and treatment approaches are presented in this article. The JAK-STAT signal pathway activation now recognized as main pathogenesis mechanism of PMF, it caused by JAK2, CALR, MPL genes mutations. Authors demons...

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Bibliographic Details
Main Authors: K. M. Abdulkadyrov, V. A. Shuvaev, I. S. Martynkevich
Format: Article
Language:Russian
Published: ABV-press 2015-06-01
Series:Onkogematologiâ
Subjects:
primary myelofibrosis
Janus kinase gene mutation
calreticulin gene mutation
prognostic scales
treatment algorithm
ruxolitinib
Online Access:http://oncohematology.abvpress.ru/index.php/ongm/article/view/142

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http://oncohematology.abvpress.ru/index.php/ongm/article/view/142

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