ATP4a Is Required for Wnt-Dependent Foxj1 Expression and Leftward Flow in Xenopus Left-Right Development
Most vertebrate embryos break symmetry by a cilia-driven leftward flow during neurulation. In the frog Xenopus asymmetric expression of the ion pump ATP4a was reported at the 4-cell stage. The “ion-flux” model postulates that symmetry is broken flow-independently through an ATP4-generated asymmetri...
| Main Authors: | , , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Elsevier
2012-05-01
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| Series: | Cell Reports |
| Online Access: | http://www.sciencedirect.com/science/article/pii/S2211124712000903 |