Analyzing Nicotinamide Adenine Dinucleotide Phosphate Oxidase Activation in Aging and Vascular Amyloid Pathology

Analyzing Nicotinamide Adenine Dinucleotide Phosphate Oxidase Activation in Aging and Vascular Amyloid Pathology

In aging individuals, both protective as well as regulatory immune functions are declining, resulting in an increased susceptibility to infections as well as to autoimmunity. Nicotinamide adenine dinucleotide phosphate (NADPH) oxidase 2-deficiency in immune cell subsets has been shown to be associat...

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Bibliographic Details
Main Authors: Helena Radbruch, Ronja Mothes, Daniel Bremer, Stefanie Seifert, Ralf Köhler, Julian Pohlan, Lennard Ostendorf, Robert Günther, Ruth Leben, Werner Stenzel, Raluca Aura Niesner, Anja E. Hauser
Format: Article
Language:English
Published: Frontiers Media S.A. 2017-07-01
Series:Frontiers in Immunology
Subjects:
aging
NADPH oxidases
microglia
astrocytes
Alzheimer’s disease
cerebral amyloid angiopathy
Online Access:http://journal.frontiersin.org/article/10.3389/fimmu.2017.00844/full

Internet

http://journal.frontiersin.org/article/10.3389/fimmu.2017.00844/full

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