Human Intravenous Immunoglobulin Alleviates Neuropathic Symptoms in a Rat Model of Paclitaxel-Induced Peripheral Neurotoxicity

Human Intravenous Immunoglobulin Alleviates Neuropathic Symptoms in a Rat Model of Paclitaxel-Induced Peripheral Neurotoxicity

The onset of chemotherapy-induced peripheral neurotoxicity (CIPN) is a leading cause of the dose reduction or discontinuation of cancer treatment due to sensory symptoms. Paclitaxel (PTX) can cause painful peripheral neuropathy, with a negative impact on cancer survivors’ quality of life. While rece...

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Bibliographic Details
Main Authors: Cristina Meregalli, Laura Monza, Alessia Chiorazzi, Carla Scali, Chiara Guarnieri, Giulia Fumagalli, Paola Alberti, Eleonora Pozzi, Annalisa Canta, Elisa Ballarini, Virginia Rodriguez-Menendez, Norberto Oggioni, Guido Cavaletti, Paola Marmiroli
Format: Article
Language:English
Published: MDPI AG 2021-01-01
Series:International Journal of Molecular Sciences
Subjects:
paclitaxel
neuropathic pain
intravenous immunoglobulin (IVIg)
chemotherapy
axon degeneration
IENF
Online Access:https://www.mdpi.com/1422-0067/22/3/1058

Internet

https://www.mdpi.com/1422-0067/22/3/1058

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