Control of protein degradation by N-terminal acetylation and the N-end rule pathway

Protein Nα-terminal acetylation: Regulating stability The addition of an acetyl group to amino acids at the start of a protein (known as the Nα-terminal end) is crucial for maintaining protein homeostasis and cellular health. Hwang and colleagues review the effects of Nα-terminal acetylation (Nt-ace...

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Bibliographic Details
Main Authors: Kha The Nguyen, Sang-Hyeon Mun, Chang-Seok Lee, Cheol-Sang Hwang
Format: Article
Language:English
Published: Nature Publishing Group 2018-07-01
Series:Experimental and Molecular Medicine
Online Access:https://doi.org/10.1038/s12276-018-0097-y