Histone Epigenetic Signatures in Embryonic Limb Interdigital Cells Fated to Die

During limb formation in vertebrates with free digits, the interdigital mesoderm is eliminated by a massive degeneration process that involves apoptosis and cell senescence. The degradation process is preceded by intense DNA damage in zones located close to methylated DNA, accompanied by the activat...

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Bibliographic Details
Main Authors: Cristina Sanchez-Fernandez, Carlos I. Lorda-Diez, Cristina Duarte-Olivenza, Juan M. Hurle, Juan A. Montero
Format: Article
Language:English
Published: MDPI AG 2021-04-01
Series:Cells
Subjects:
Online Access:https://www.mdpi.com/2073-4409/10/4/911