Evolution game: which came first, the receptor or the ligand?

On the basis of a bioinformatic approach, we suggest that in invertebrates many ligands interact with a single, ancestral and generalized receptor driving ligand evolution. In vertebrates, on the other hand, the occurrence of gene/genome duplications induced the shift to a ligand-directed evolution...

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Bibliographic Details
Main Authors: M Mandrioli, D Malagoli, E Ottaviani
Format: Article
Language:English
Published: University of Modena and Reggio Emilia 2007-04-01
Series:Invertebrate Survival Journal
Subjects:
Online Access:https://isj02.unimore.it/index.php/ISJ/article/view/142