Evolution game: which came first, the receptor or the ligand?
On the basis of a bioinformatic approach, we suggest that in invertebrates many ligands interact with a single, ancestral and generalized receptor driving ligand evolution. In vertebrates, on the other hand, the occurrence of gene/genome duplications induced the shift to a ligand-directed evolution...
Main Authors: | M Mandrioli, D Malagoli, E Ottaviani |
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Format: | Article |
Language: | English |
Published: |
University of Modena and Reggio Emilia
2007-04-01
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Series: | Invertebrate Survival Journal |
Subjects: | |
Online Access: | https://isj02.unimore.it/index.php/ISJ/article/view/142 |
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