MALDI Mass Spectrometry Imaging Linked with Top-Down Proteomics as a Tool to Study the Non-Small-Cell Lung Cancer Tumor Microenvironment

MALDI Mass Spectrometry Imaging Linked with Top-Down Proteomics as a Tool to Study the Non-Small-Cell Lung Cancer Tumor Microenvironment

Advanced non-small-cell lung cancer (NSCLC) is generally linked with a poor prognosis and is one of the leading causes of cancer-related deaths worldwide. Since only a minority of the patients respond well to chemotherapy and/or targeted therapies, immunotherapy might be a valid alternative in the l...

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Bibliographic Details
Main Authors: Eline Berghmans, Geert Van Raemdonck, Karin Schildermans, Hanny Willems, Kurt Boonen, Evelyne Maes, Inge Mertens, Patrick Pauwels, Geert Baggerman
Format: Article
Language:English
Published: MDPI AG 2019-05-01
Series:Methods and Protocols
Subjects:
NSCLC
MALDI mass spectrometry imaging
tissue preparation
Carnoy’s washing procedure
high resolution mass spectrometry
top-down
endogenous peptides
Online Access:https://www.mdpi.com/2409-9279/2/2/44

Internet

https://www.mdpi.com/2409-9279/2/2/44

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