Effect of fluid shear stress on the internalization of kidney-targeted delivery systems in renal tubular epithelial cells

Renal tubular epithelial cells (RTECs) are important target cells for the development of kidney-targeted drug delivery systems. Under physiological conditions, RTECs are under constant fluid shear stress (FSS) from original urine in the renal tubule and respond to changes of FSS by altering their mo...

Full description

Bibliographic Details
Main Authors: Yingying Xu, Shuo Qin, Yining Niu, Tao Gong, Zhirong Zhang, Yao Fu
Format: Article
Language:English
Published: Elsevier 2020-04-01
Series:Acta Pharmaceutica Sinica B
Online Access:http://www.sciencedirect.com/science/article/pii/S2211383519307683