Potential Utility of Protein Targets of Cysteine-S-Nitrosylation in Identifying Clinical Disease Status in Human Chagas Disease

Potential Utility of Protein Targets of Cysteine-S-Nitrosylation in Identifying Clinical Disease Status in Human Chagas Disease

Trypanosoma cruzi (Tc) infection causes Chagas disease (ChD) presented by dilated cardiomyopathy and heart failure. During infection, oxidative and nitrosative stresses are elicited by the immune cells for control the pathogen; however, excess nitric oxide and superoxide production can result in cys...

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Bibliographic Details
Main Authors: Maria Paola Zago, John E. Wiktorowicz, Heidi Spratt, Sue-Jie Koo, Natalia Barrientos, Aida Nuñez Burgos, Julio Nuñez Burgos, Facundo Iñiguez, Valentina Botelli, Ricardo Leon de la Fuente, Nisha Jain Garg
Format: Article
Language:English
Published: Frontiers Media S.A. 2019-01-01
Series:Frontiers in Microbiology
Subjects:
infectious disease
Chagas cardiomyopathy
Trypanosoma cruzi
S-nitrosylation
peripheral blood mononuclear cells
2DE
Online Access:https://www.frontiersin.org/article/10.3389/fmicb.2018.03320/full

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https://www.frontiersin.org/article/10.3389/fmicb.2018.03320/full

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