HER2-antigen-specific humoral immune response in breast cancer lymphocytes transplanted in hu-PBL hIL-4 NOG mice

HER2-antigen-specific humoral immune response in breast cancer lymphocytes transplanted in hu-PBL hIL-4 NOG mice

Abstract The status of humoral immunity of cancer patients is not clear compared to cellular immunity because the ability of specific antibody production is difficult to analyze in vitro. We previously developed a humanized mouse model to evaluate antigen-specific antibody production by transplantin...

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Bibliographic Details
Main Authors: Yusuke Ohno, Shino Ohshima, Asuka Miyamoto, Fuyuki Kametani, Ryoji Ito, Banri Tsuda, Yukie Kasama, Shunsuke Nakada, Hirofumi Kashiwagi, Toshiro Seki, Atsushi Yasuda, Kiyoshi Ando, Mamoru Ito, Yutaka Tokuda, Yoshie Kametani
Format: Article
Language:English
Published: Nature Publishing Group 2021-06-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-021-92311-y

Internet

https://doi.org/10.1038/s41598-021-92311-y

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