Molecular Profiling of Druggable Targets in Clear Cell Renal Cell Carcinoma Through Targeted RNA Sequencing

Molecular Profiling of Druggable Targets in Clear Cell Renal Cell Carcinoma Through Targeted RNA Sequencing

Clear cell renal cell carcinoma (ccRCC) comprises more than 80% of all renal cancers and when metastasized leads to a 5-year survival rate of only 10%. The high rate of therapy failure and resistance development calls for reliable methods that provide information on the actionable biological pathway...

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Bibliographic Details
Main Authors: Corina N. A. M. van den Heuvel, Anne van Ewijk, Carolien Zeelen, Tessa de Bitter, Martijn Huynen, Peter Mulders, Egbert Oosterwijk, William P. J. Leenders
Format: Article
Language:English
Published: Frontiers Media S.A. 2019-03-01
Series:Frontiers in Oncology
Subjects:
cancer
renal cell carcinoma
diagnostics
prognostics
precision therapy
RNA-sequencing
Online Access:https://www.frontiersin.org/article/10.3389/fonc.2019.00117/full

Internet

https://www.frontiersin.org/article/10.3389/fonc.2019.00117/full

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